What is Trisomy-21

Trisomy 21, also known as Down syndrome, is a naturally occurring genetic condition. It happens when a person is born with three copies of chromosome 21 instead of the usual two. That extra copy of genetic information can affect development, but it’s also what makes each person with Down syndrome unique.

Understanding the Basics

Every cell in our body contains chromosomes — tiny packages of DNA that carry our genes. Most people have 46 chromosomes, arranged in 23 pairs. Individuals with Trisomy 21 have 47 chromosomes, because of the extra copy of chromosome 21.

This difference can influence learning, growth, and physical traits, but it doesn’t define who someone is. People with Down syndrome lead full, active, and meaningful lives — as students, athletes, artists, and friends.

Common Traits

While everyone with Trisomy 21 is different, some common characteristics may include:

• Distinctive facial features
• Lower muscle tone (especially in infancy)
• Learning differences (usually mild to moderate)
• Possible heart, thyroid, or vision challenges — often treatable with proper care

What Matters Most

Having Down syndrome doesn’t limit potential. With support, inclusion, and opportunity, people with Trisomy 21 achieve amazing things every day. At WEMBELIEVE, we celebrate that — helping athletes with disabilities, and those competing in their honor, cross their own finish lines.